Circulatory Systems (Cambridge International A-Level Biology)
Closed Double Circulatory System
Spec point —
8.1.1· state that the mammalian circulatory system is a closed double circulation consisting of a heart, blood and blood vessels including arteries, arterioles, capillaries, venules and veins
The need for a circulatory system
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The cells of all living organisms need a constant supply of reactants for metabolism, e.g. oxygen and glucose
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Single celled organisms can gain oxygen and glucose directly from their surroundings
- The molecules can diffuse to all parts of the cell quickly due to short diffusion distances
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Larger organisms, however, are made up of many layers of cells
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This means that the time taken for substances such as glucose and oxygen to diffuse to every cell in the body would be far too long
- The diffusion distances involved are too great
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To solve this problem their exchange surfaces are connected to a mass transport system, for example
- The digestive system is connected to the circulatory system
- The lungs are connected to the circulatory system
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Mass transport is the bulk movement of gases or liquids in one direction, usually via a system of vessels and tubes
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The circulatory system in mammals is a well-studied example of a mass transport system
- The one-way flow of blood within the blood vessels carries essential nutrients and gases to all the cells of the body
Open and closed systems
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Circulatory systems are either described as being open or closed
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In a closed circulatory system, blood is pumped around the body and is always contained within a network of blood vessels
- All vertebrates and many invertebrates have closed circulatory systems
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In an open circulatory system, blood is not contained within blood vessels but is pumped directly into body cavities
- Organisms such as arthropods and molluscs have open circulatory systems
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Humans have a closed double circulatory system:
- In one complete circuit of the body blood passes through the heart (the pump) twice
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The right side of the heart pumps deoxygenated blood to the lungs for gas exchange
- This is the pulmonary circulatory system
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Blood then returns to the left side of the heart, so that oxygenated blood can be pumped efficiently (at high pressure) around the body
- This is the systemic circulatory system

The double circulatory system in mammals showing pulmonary and systemic circulation
| Structure | Function |
|---|---|
| Heart | A hollow, muscular organ located in the chest cavity which pumps blood. Cardiac muscle tissue is specialised for repeated involuntary contraction without rest. |
| Arteries | Blood vessels which carry blood away from the heart. The walls of the arteries contain lots of muscle and elastic tissue and a narrow lumen, to maintain high blood pressure. |
| Arterioles | Small arteries which branch from larger arteries and connect to capillaries. |
| Capillaries | Tiny blood vessels which connect arterioles and venules. Their size means they pass directly past cells and tissues and perform gas exchange and exchange of substances such as glucose. |
| Venules | Small veins which join capillaries to larger veins. |
| Veins | Blood vessels which carry blood back towards the heart. The walls of veins are thin in comparison to arteries, having less muscle and elastic tissue but a wider lumen. Valves help maintain blood flow back towards the heart. |
Exam Hint Make sure you study any circulatory diagrams in the exam carefully to distinguish between single and double circulatory systems.
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